Liu, Zihe


NameZihe Liu


AddressBeijing University of Chemical Biology

Education background:

2002-2006, Undergraduate of Tianjin University. 
2006-2008, Master student of Tianjin University. 

2008-2012, PhD student of Chalmers University of Technology, Sweden. 

Work experience :

2013-2017, Scientist I of Agency for Science, and Technology and Research, Singapore.
 2017 to 2021, Associate Professor of Beijing University of Chemical Technology, China.

2021-, Professor of Beijing University of Chemical Technology, China.

Academic title: Professor

Research areas: Synthetic biology, Metabolic Engineering, Systems Biology

Honors and awards:

2017      Biosystems Design 3.0 best poster awards

2011      FEBS Youth Travel Fund

2010      FEBS Gothenburg Fund

2019      Nils Pihlblads resestipendium

Research projects: Synthetic biology and metabolic engineering of yeast S. cerevisiae for production of fuels, chemicals and natural products

Representative works:

1.    Liu Z, Wang K, Chen Y, Tan T#, Nielsen J#. Third-generation biorefineries as the means to produce fuels and chemicals from CO2. Nature Catalysis, 2020, 3: 274-288. (TOP)

2.    Zhang Y*, Wang J*, Wang Z, Zhang Y, Shi S, Nielsen J, Liu Z. A gRNA-tRNA array for CRISPR-Cas9 based rapid multiplexed genome editing in Saccharomyces cerevisiae. Nature Communications, 2019, 10: 1053. (TOP)

3.    Gong G*, Zhang Y*, Wang Z, Liu L, Shi S, Siewers V, Yuan Q, Nielsen J, Zhang X#, Liu Z#. GTR 2.0: gRNA-tRNA array and Cas9-NG based genome disruption and dingle-nucleotide conversion in Saccharomyces cerevisiae. ACS Synthetic Biology, 2021, DOI: 10.1021/acssynbio.0c00560. (TOP)

4.    Liu Z, Moradi H, Shi S#, Darvishi F#. Yeasts as microbial cell factories for sustainable production of biofuels. Renewable & Sustainable Energy Reviews, 2021, 143: 110907 (TOP)

5.    Zhao Y, Zhang Y, Nielsen J, Liu Z. Production of β-carotene in Saccharomyces cerevisiae through altering yeast lipid metabolism. Biotechnology and Bioengineering, 2021, 118: 2043-2052 (TOP)

6.    Liu Z, Lin Z, Nielsen J. Expression of fungal biosynthetic gene clusters in S. cerevisiae for natural product discovery. Synthetic and Systems Biotechnology, 2021. 6: 20-22.

7.    Zhang Y, Nielsen J#, Liu Z#. Yeast based biorefineries for oleochemical production. Current Opinion in Biotechnology, 2021. 67: 26-34. (TOP)

8.    李祎, 林振泉#, 刘子鹤#. 酿酒酵母适应性实验室进化工具的最新进展. 合成生物学, 2021. 2 (2): 287-301

9.    Zhang Y*, Su M*, Qin N, Nielsen J, Liu Z. Expressing a cytosolic pyruvate dehydrogenase complex to increase free fatty acid production in Saccharomyces cerevisiae, Microbial Cell Factories, 2020, 19(1): 226.

10.  Qin N*, Li L*, Ji X, Li X, Zhang Y, Larsson C, Chen Y, Nielsen J, Liu Z. Rewiring central carbon metabolism ensures increased provision of acetyl-CoA and NADPH required for 3-OH-propionic acid production. ACS Synthetic Biology, 2020, 9: 3236-3244. (TOP)

11.  Lin Z, Nielsen J, Liu Z. Bioprospecting through cloning of whole natural product biosynthetic gene clusters. Frontiers in Bioengineering and Biotechnology, 2020, 8526.

12.  Liu Z, Zhang Y, Nielsen J. Synthetic biology of yeast. Biochemistry, 2019, 58: 1511-1520.

13.  Zhang Y, Nielsen J, Liu Z. Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid-derived hydrocarbons. Biotechnology and Bioengineering, 2018, 115 (9): 2139-2147. (TOP)

Admission requirements:

Honest, innovative and hard working