Systems Metabolic Engineering and Al-Assisted Biotechnology

Date:2026-09-17

Green Biomanufacturing Lecture Series

Academic Lecture Series, Session 2, 2026


Time: Friday, September 18, 2026, 15:00

Location: 3rd Floor Academic Lecture Hall, Conference Center, East Campus, Beijing University of Chemical Technology


Speaker Introduction:

Sang Yup Lee

Director, Center for Synthetic Biology, KAIST

President, Korea Synthetic Biology Association

Fellow of the Korean Academy of Science and Technology, Korea

Foreign Academician of the Chinese Academy of Engineering, China

International Member of the National Academy of Sciences, USA

Fellow of the European Academy of Microbiology, Europe


Abstract:

The growing demand for sustainable production of chemicals, materials, fuels, foods, and pharmaceuticals is accelerating the transition from conventional petrochemical manufacturing toward biological manufacturing. Systems metabolic engineering, which integrates metabolic engineering with systems biology, synthetic biology, and evolutionary engineering, provides a powerful framework for developing microbial cell factories capable of producing diverse molecules with high efficiency. Over the past decades, this approach has enabled the production of numerous industrial chemicals and materials, including amino acids, organic acids, diamines, diols, polymers, natural products, and pharmaceuticals, with several processes reaching industrially relevant performance. In this lecture, I will present recent advances in systems metabolic engineering for developing high-performance microbial strains and bioprocesses. I will also discuss Al-assisted studies of drug-drug interactions in the context of future opportunities in biotechnology.